Description
Rejuran-i is a highly specialized version of the Rejuran PN (Polynucleotide) family, specifically engineered for the delicate skin around the eyes. While the standard Rejuran Healer is designed for the entire face, Rejuran-i (the “i” stands for Eye) has a lower viscosity and smoother consistency. This allows for safe, superficial injection into the thin skin of the periorbital region without the risk of creating long-lasting lumps or heavy edema. It acts as a biological repair stimulator, targeting dark circles, hollows, and “crow’s feet” by thickening the dermal structure from within.
Main Benefits of Rejuran-i
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Targeted Periorbital Repair: Specifically formulated to treat the thinnest skin on the body, providing structural reinforcement where traditional fillers might be too heavy or visible.
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Dark Circle Reduction: Improves microcirculation and increases dermal thickness, which helps mask the underlying blood vessels and pigments that cause dark circles.
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Crow’s Feet & Fine Lines: Smooths out fine wrinkles around the eyes by stimulating natural collagen and elastin production.
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Volume Restoration: Gently fills the “tear trough” hollows by encouraging the skin to regenerate its own tissue density rather than simply adding a synthetic volume.
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Low Viscosity for Safety: The fluid nature of the gel ensures rapid absorption and seamless integration into the delicate eye tissue, minimizing downtime and post-injection papules.
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High Bio-Compatibility: Derived from salmon DNA fragments, it is non-immunogenic and exceptionally safe for the sensitive eye area.
Indications
Rejuran-i is the premier choice for patients seeking a natural rejuvenation of the gaze:
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Under-Eye Hollows: Treating the “tired look” caused by thinning skin and tear trough depressions.
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Dark Under-Eye Circles: Brightening the periorbital area by improving skin health and opacity.
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Fine Wrinkles: Correcting “crow’s feet” and fine dehydration lines around the eyelids.
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Elasticity Loss: Tightening sagging skin on the lower and upper eyelids.
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Post-Laser Recovery: Accelerating the healing process after fractional laser or plasma treatments in the eye area.
Technical Specifications
| Feature | Specification |
| Product Name | Rejuran-i |
| Manufacturer | PharmaResearch Products (South Korea) |
| Active Ingredient | Polynucleotide (PN) 1% |
| Viscosity | Low (Optimized for thin skin) |
| Packaging | 1 x 1ml Pre-filled syringe |
| Needle Size | 34G ultra-fine needle included |
| Injection Depth | Superficial dermis (intradermal) |
| Storage | Store at room temperature (1°C to 30°C) |
Mechanism of Action
Rejuran-i works through Biological Tissue Scaffolding:
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Dermal Thickening: The PN fragments provide a template for cellular repair, signaling the body to increase the production of the extracellular matrix.
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Vascular Support: By strengthening the surrounding tissue, it provides better support to the fragile capillaries around the eyes, reducing fluid leakage and dark shadows.
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Anti-Inflammatory Action: PN molecules help calm the sensitive periorbital skin, reducing chronic low-grade inflammation that contributes to aging.
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Natural Integration: Unlike Hyaluronic Acid, which can attract too much water (leading to morning puffiness), PN integrates into the skin’s biology to improve quality without changing the water balance.
Administration Protocol
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Technique: Micro-droplet or “nappage” technique using an ultra-fine 34G needle.
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Depth: Injected very superficially into the intradermal layer of the lower and upper eyelids.
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Treatment Cycle: For optimal results, a course of 3 sessions is recommended, spaced 4 weeks apart.
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Maintenance: A single maintenance session every 6 to 9 months helps preserve the regenerative effects.
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Professional Note: Because the skin is so thin, small papules will be visible immediately after treatment. Due to the low viscosity of Rejuran-i, these typically resolve within 12 to 24 hours.
FAQ
Q: How is Rejuran-i different from Rejuran Healer?
A: Rejuran Healer has a 2% PN concentration and higher viscosity for the whole face. Rejuran-i has a 1% concentration and a “thinner” consistency, making it safer and more effective for the thin, delicate skin around the eyes.
Q: Does it help with under-eye bags?
A: It is excellent for “hollow” bags (tear troughs) and skin laxity. However, if the bags are caused by protruding fat pads (herniated fat), surgery or different treatments may be required, though Rejuran-i can still improve the skin quality over the area.
Q: Will it cause swelling?
A: Some minor swelling is expected for the first 24 hours. However, Rejuran-i is much less likely to cause the prolonged “Tyndall effect” or persistent edema often seen with HA fillers in the eye area.
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