Description
Rejuran S (Scar) is a more concentrated and viscous version of the Rejuran Polynucleotide (PN) family, specifically developed for the treatment of depressed scars and deep skin indentations. While other products in the line focus on general rejuvenation or delicate areas, Rejuran S is engineered to provide structural “filler-like” support while simultaneously triggering long-term biological tissue repair. Derived from salmon DNA fragments, it is the premier non-surgical solution for smoothing acne scars, surgical marks, and skin irregularities by inducing the growth of new, healthy dermal tissue.
Main Benefits of Rejuran S
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Targeted Scar Filling: Its higher viscosity allows it to sit precisely under a depressed scar, providing immediate physical elevation of the skin surface.
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Intensive Tissue Regeneration: PN molecules act as a biological scaffold, stimulating fibroblasts to produce new collagen and healthy skin cells to fill the indentation over time.
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Acne Scar Specialist: Particularly effective for “boxcar” and “rolling” acne scars, which require both structural support and skin remodeling.
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Biological Compatibility: The salmon-derived PN is highly compatible with human skin, ensuring a safe treatment with minimal risk of granulomas or allergic reactions.
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Long-Lasting Skin Smoothing: Unlike temporary fillers, the improvements seen with Rejuran S are due to actual tissue repair, leading to more permanent results as the skin’s architecture is restored.
Indications
Rejuran S is the optimal choice for localized skin repair:
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Depressed Acne Scars: Filling and smoothing “ice pick,” “boxcar,” and “rolling” scars.
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Surgical & Trauma Scars: Improving the texture and appearance of old or indented surgical marks.
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Deep Skin Furrows: Addressing specific deep wrinkles that require more structural support than standard skin boosters.
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Skin Indentations: Treating any localized area where the dermal layer has thinned or collapsed.
Technical Specifications
| Feature | Specification |
| Product Name | Rejuran S |
| Manufacturer | PharmaResearch Products (South Korea) |
| Active Ingredient | Polynucleotide (PN) 2% |
| Viscosity | High (Optimized for localized scar support) |
| Packaging | 1 x 1ml Pre-filled syringe |
| Needle Size | 30G needle included |
| Injection Depth | Deep dermis (directly under the scar) |
| Storage | Store at room temperature (1°C to 30°C) |
Mechanism of Action
Rejuran S works through Mechanical Support & Biological Induction:
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Immediate Volume: Upon injection, the viscous gel provides a mechanical lift to the depressed scar, instantly making the skin surface appear more even.
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Cellular Signaling: The PN fragments bind to receptors on fibroblast cells, signaling them to accelerate the production of Type I and Type III collagen.
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DNA Synthesis Support: It provides the building blocks (nucleotides) for new skin cells, facilitating rapid tissue repair in areas where the skin has been damaged.
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Extracellular Matrix (ECM) Remodeling: Over several weeks, the injected PN is replaced by the patient’s own healthy collagen, resulting in a naturally smooth skin texture.
Administration Protocol
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Technique: Usually administered via serial puncture or linear threading directly underneath each individual scar.
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Combination Therapy: For severe acne scarring, Rejuran S is often combined with subcision (breaking the fibrous bands under the scar) or fractional laser treatments to maximize the regenerative effect.
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Treatment Cycle: A course of 3 to 4 sessions is typically recommended, spaced 4 weeks apart.
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Recovery: Localized swelling or minor bruising at the injection sites may occur but typically resolves within 2–3 days.
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Professional Note: Because of its higher viscosity, Rejuran S should not be used for general facial skin boosting; it is strictly intended for localized depressions.
FAQ
Q: How is Rejuran S different from Rejuran Healer?
A: Rejuran Healer is more fluid and designed for the whole face to improve general skin quality. Rejuran S is much thicker (more viscous), making it suitable for staying in place under a scar to provide physical support and localized healing.
Q: Are the results permanent?
A: Because Rejuran S stimulates the body to grow its own new skin tissue and collagen, the improvements in scar depth and texture are significantly more durable than those achieved with temporary HA fillers.
Q: Can I use it on fresh scars?
A: It is best used on mature, healed scars. For very recent scars, it is recommended to wait until the initial healing phase is complete before starting regenerative PN therapy.
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