Description
Ellansé M is a revolutionary dual-action dermal filler that belongs to a unique class of regenerative aesthetics. Developed by Sinclair, it differs from traditional hyaluronic acid fillers by using Polycaprolactone (PCL) microspheres suspended in a tailored carboxymethylcellulose (CMC) gel carrier. This “Biostimulator” not only provides immediate volume correction but also triggers the body’s natural production of Type I collagen. The “M” version is specifically designed for patients seeking a mid-term duration of effect, offering stable results for up to two years.
Main Benefits of Ellansé M
Immediate Correction & Long-Term Regrowth
Ellansé M provides a “two-step” transformation. The CMC gel carrier offers instant volumization upon injection. As the gel is gradually absorbed by the body, the PCL microspheres remain, acting as a scaffold that stimulates fibroblasts to produce high-quality collagen, ensuring the volume is maintained by the patient’s own tissue.
Tunable Longevity
The Ellansé range is unique because the duration of the effect is pre-determined by the length of the PCL polymer chains. Ellansé M is formulated to last for 24 months, providing a cost-effective and convenient solution for patients who want long-lasting rejuvenation without frequent top-ups.
Total Bio-Resorbability
Unlike permanent implants, Ellansé M is 100% bio-resorbable. The PCL microspheres are slowly broken down into Co2 and water via the body’s natural metabolic pathways, ensuring an excellent safety profile and predictable degradation over the two-year period.
High Elasticity and Viscosity
The rheological properties of Ellansé M make it exceptionally stable. It stays exactly where it is placed, resisting migration and providing a “Statuesque” lift that is ideal for defining facial contours like the jawline and chin.
Indications
Ellansé M is designed for deep dermal and sub-dermal placement to treat:
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Mid-Face Volumization: Restoring fullness to the cheeks and malar area.
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Temple Rejuvenation: Filling deep hollows in the upper face.
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Lower Face Sculpting: Defining a sharp jawline and enhancing chin projection.
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Nasolabial Folds: Smoothing deep lines by addressing the underlying volume loss.
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Hand Rejuvenation: Restoring a youthful appearance to the back of the hands.
Technical Specifications
| Feature | Specification |
| Product Name | Ellansé M |
| Manufacturer | Sinclair (UK/The Netherlands) |
| Composition | 30% PCL Microspheres / 70% CMC Gel Carrier |
| Technology | Tunable Longevity Technology |
| Packaging | 2 x 1ml Pre-filled syringes |
| Included Needles | 4 sterile needles (27G ¾) |
| Injection Depth | Subcutaneous or deep dermis |
| Duration | Up to 24 months |
Mechanism of Action
Ellansé M works through Collagen Stimulation (Neocollagenesis):
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Instant Filling: The CMC gel carrier fills the skin depressions immediately after treatment.
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Bio-Stimulation: Within weeks, the PCL microspheres stimulate the body’s natural inflammatory response (at a microscopic, safe level) to wrap the spheres in new collagen.
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Enduring Results: As the PCL spheres slowly dissolve over 24 months, the newly formed collagen network maintains the structure and elasticity of the skin.
Administration Protocol
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Technique: Fanning or linear retrograde. The use of a cannula is highly recommended to ensure even distribution and minimize bruising.
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Depth: Must be injected into the subcutaneous tissue or deep dermis. It should never be injected superficially.
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Professional Note: Unlike HA fillers, Ellansé is not reversible with hyaluronidase. Precise placement and conservative dosing are essential. Do not over-correct.
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Post-Care: Avoid vigorous facial massage, extreme heat, and heavy exercise for 3 days to allow the product to settle.
FAQ
Q: Can Ellansé M be dissolved?
A: No. Because it is not a hyaluronic acid filler, it cannot be dissolved with hyaluronidase. It is critical that it is administered by an experienced professional.
Q: Is it suitable for the lips or under-eye area?
A: No. Ellansé M should not be used in the lips or the tear trough area (under the eyes) due to the risk of nodules and the thin nature of the skin in those regions.
Q: When will I see the final results?
A: While you see an immediate improvement from the gel carrier, the “true” regenerative results from collagen stimulation become most apparent between 3 to 4 months post-treatment.






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