Introduction: What is Xeomin 100iu?

Xeomin 100iu is a botulinum toxin type A preparation developed by Merz Pharmaceuticals. It is an advanced neuromodulator used in both aesthetic medicine and therapeutic applications. Like other botulinum toxin products, Xeomin works by temporarily relaxing targeted muscles, reducing the appearance of dynamic wrinkles, or alleviating muscle overactivity. What sets Xeomin apart is its uniquely purified formulation—completely free of complexing proteins, offering a “naked” neurotoxin solution that minimizes the potential for immune response or resistance over time.

Delivered in a 100-unit vial, Xeomin is an injectable solution indicated for a variety of cosmetic and medical treatments. It is FDA-approved and widely used by licensed healthcare professionals around the world.

Key Features & Benefits

1. Unique Purity with No Additives

Xeomin is the only botulinum toxin on the market that contains nothing but the active ingredient—botulinum toxin type A. Unlike its competitors, Xeomin undergoes a proprietary purification process that eliminates complexing proteins. This results in a product that is less likely to provoke an immune reaction, which is especially beneficial for patients receiving repeat treatments.

2. Proven Efficacy

Clinical studies and years of application in both aesthetic and therapeutic fields have demonstrated Xeomin’s effectiveness in managing glabellar lines (frown lines between the eyebrows), blepharospasm (uncontrollable blinking), cervical dystonia (abnormal neck movements), and other neuromuscular conditions. In aesthetic applications, Xeomin yields natural-looking results that appear gradually and last for several months.

3. High Precision Formulation

Because Xeomin contains no unnecessary proteins or additives, it allows physicians to administer precise doses with predictable outcomes. This ensures optimal control over treatment areas and minimizes the risk of spread to adjacent muscles.

4. Room Temperature Stability Before Reconstitution

Unlike other botulinum toxins that require constant refrigeration, Xeomin offers more flexible storage options. In its lyophilized (powder) form, Xeomin remains stable at room temperature before it is reconstituted with saline solution. This feature is particularly convenient for clinics, mobile practitioners, and global distributors.

5. Consistent Results

The consistent molecular profile and absence of complexing proteins allow Xeomin to provide reliable results over repeated treatment sessions. This makes it a dependable choice for long-term patients and medical practices that prioritize consistency and safety.

Aesthetic Applications of Xeomin 100iu

1. Glabellar Lines

Xeomin is FDA-approved for the temporary improvement of moderate to severe glabellar lines—those vertical frown lines between the eyebrows that result from repeated muscle contractions. Within 3 to 5 days of injection, patients begin to see a smoother and more relaxed appearance, with full results typically visible within two weeks.

2. Forehead Lines and Crow’s Feet

Though not officially indicated for these areas in all countries, Xeomin is widely used off-label by experienced practitioners to treat horizontal forehead lines and crow’s feet (lines around the outer corners of the eyes). Its precision and clean formulation make it a favorite for achieving a natural, expressive look without a “frozen” effect.

3. Brow Lift and Facial Contouring

Xeomin can also be used to subtly lift the brows by relaxing the muscles that pull them downward. When applied with skill, it enhances the shape of the face and creates a refreshed, youthful appearance. Similarly, Xeomin is used in facial contouring treatments to soften masseter muscles (jawline slimming) and address dimpling in the chin.

4. Hyperhidrosis Treatment

Though more commonly associated with Botox for excessive sweating, Xeomin can also be used to reduce sweating in areas like the underarms, palms, and feet. By blocking the nerve signals that stimulate sweat glands, Xeomin helps patients regain comfort and confidence in daily life.

Therapeutic Applications of Xeomin 100iu

1. Cervical Dystonia

Xeomin is approved for the treatment of cervical dystonia in adults—a condition characterized by involuntary contractions of the neck muscles. By relaxing the overactive muscles, Xeomin helps relieve pain, stiffness, and abnormal head postures.

2. Blepharospasm

This condition causes uncontrollable blinking or spasm of the eyelid muscles. Xeomin provides relief by targeting the affected muscles and reducing their abnormal contractions. Its pure composition makes it ideal for patients with long-term therapeutic needs.

3. Sialorrhea (Excessive Drooling)

Xeomin is also approved in some markets for treating sialorrhea, a condition often caused by neurological disorders like Parkinson’s disease. It works by inhibiting the release of acetylcholine, reducing the activity of the salivary glands.

4. Spasticity

Although more research is ongoing, Xeomin is increasingly used in the management of spasticity—tight or stiff muscles caused by conditions like stroke, cerebral palsy, or multiple sclerosis. It helps improve mobility and comfort by reducing muscle hyperactivity.

How Xeomin Works

Xeomin works by targeting the neuromuscular junction, where nerves communicate with muscles via the release of a neurotransmitter called acetylcholine. Botulinum toxin type A inhibits this release, thereby preventing the muscle from contracting. As a result, the treated muscle temporarily relaxes, softening dynamic wrinkles or alleviating spasms and other involuntary movements.

This effect is temporary, lasting between 3 to 6 months depending on the individual, the dose administered, and the muscle treated. With repeated treatments, many patients report increasingly smooth and lasting outcomes.

Dosage and Administration

Xeomin 100iu comes as a lyophilized powder in a single-use vial. It must be reconstituted with sterile, preservative-free saline before use. Dosage varies depending on the indication, muscle mass, and individual patient factors.

For aesthetic treatments like glabellar lines, a typical total dose is 20 units, distributed among 5 injection sites. For therapeutic uses, the dosage may vary significantly—ranging from 30 to over 100 units, depending on the severity and extent of the condition.

Important: Xeomin must only be administered by licensed medical professionals trained in its use. Proper anatomical knowledge and injection technique are crucial to avoid complications.

Storage and Handling

• Store Xeomin in the original carton to protect it from light.

• Unopened vials can be stored at room temperature (up to 25°C) before reconstitution.

• After reconstitution, Xeomin should be stored in a refrigerator (2°C to 8°C) and used within 24 hours.

• Do not freeze reconstituted product.

• Do not shake the vial; gently swirl to mix.

Possible Side Effects

As with all botulinum toxin products, Xeomin may cause side effects. These are usually mild and temporary but can vary based on the site of injection and patient sensitivity.

Common Side Effects Include:

• Injection site pain or redness

• Headache

• Eyelid ptosis (drooping)

• Dry eyes or blurred vision

• Neck pain (therapeutic use)

• Dysphagia (difficulty swallowing)

Rare But Serious Effects May Include:

• Muscle weakness beyond the treatment area

• Allergic reactions

• Breathing difficulties (when injected near the neck or chest)

Patients should always disclose their full medical history to the treating professional before undergoing Xeomin treatment.

Who Should Not Use Xeomin?

Xeomin is not recommended for:

• Individuals with a known allergy to botulinum toxin

• Patients with neuromuscular disorders such as myasthenia gravis or Lambert-Eaton syndrome

• Pregnant or breastfeeding women (unless directed by a doctor)

• Anyone with an active infection at the injection site

Why Choose Xeomin Over Other Botulinum Toxins?

While products like Botox® and Dysport® have long dominated the market, Xeomin presents a powerful alternative with several distinct advantages:

• Minimal risk of resistance: due to its “naked” neurotoxin structure.

• Consistent results: ideal for long-term treatment plans.

• Less chance of allergic reaction: thanks to fewer ingredients.

• More flexible storage: doesn’t require immediate refrigeration before reconstitution.

Clinics and professionals who value precision, purity, and performance increasingly make Xeomin their product of choice.

Conclusion

Xeomin 100iu stands at the cutting edge of botulinum toxin therapy. Its pure, efficient formulation and proven efficacy make it a reliable tool for practitioners and a trusted solution for patients seeking either aesthetic enhancement or relief from neuromuscular conditions. Whether smoothing lines or easing spasticity, Xeomin delivers results with integrity, precision, and safety.

In a world of cosmetic and therapeutic options, Xeomin offers clarity and confidence—one injection at a time.