Jeuveau 100 IU – Precision in Aesthetic Excellence
Category: Botulinum Toxin Type A
Brand Name: Jeuveau
Active Ingredient: PrabotulinumtoxinA-xvfs
Dosage Strength: 100 Units
Form: Lyophilized powder for solution for injection
Intended Use: Aesthetic treatment of moderate to severe glabellar lines
Product Overview
Jeuveau 100 IU represents a new evolution in aesthetic medicine, offering a modern, high-purity botulinum toxin formulation specifically designed to treat dynamic facial wrinkles. Developed by Evolus, Jeuveau is the first aesthetic-only neurotoxin approved by the FDA in the United States, and it has quickly gained popularity among medical professionals and patients for its performance, safety, and affordability.
Jeuveau is formulated using a unique proprietary purification process known as Hi-Pure™ technology. This advanced method helps ensure a highly refined and consistent product that delivers reliable clinical outcomes with minimal impurities. With Jeuveau 100 IU, practitioners can confidently offer patients a non-surgical solution for smoothing expression lines, particularly glabellar lines—commonly known as frown lines between the eyebrows.
Key Features and Benefits
FDA-Approved for Cosmetic Use
Jeuveau is specifically approved for aesthetic indications, making it the first and only botulinum toxin launched exclusively for cosmetic applications in the U.S.High Purity, Consistent Results
Thanks to its Hi-Pure™ technology, Jeuveau is free from unnecessary proteins and impurities, which contributes to more predictable results and a reduced risk of immunogenicity.Fast Onset and Long-Lasting Effects
Clinical studies have shown that Jeuveau provides noticeable wrinkle reduction within just a few days, with results that typically last 3 to 5 months.Comparable Efficacy to Botox
Jeuveau has demonstrated non-inferiority to Botox in FDA clinical trials, making it a trusted alternative for aesthetic practitioners seeking a competitive edge.More Affordable Without Sacrificing Quality
Designed with price-conscious practices and patients in mind, Jeuveau offers premium results at a more accessible cost, making cosmetic treatments more widely available.
Clinical Indications
Jeuveau 100 IU is indicated for the temporary improvement in the appearance of moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity in adult patients.
Off-label applications are commonly practiced by qualified healthcare providers and may include the treatment of:
Horizontal forehead lines
Crow’s feet (lateral canthal lines)
Bunny lines on the nose
Chin dimpling
Neck bands
Jawline slimming (masseter reduction)
Brow lifting
Note: Any off-label use should be carried out by licensed professionals with appropriate training and informed patient consent.
Composition
Each vial of Jeuveau contains:
PrabotulinumtoxinA-xvfs – 100 units
Human albumin – 0.5 mg
Sodium chloride – 0.9 mg
The product is supplied as a sterile, vacuum-dried powder in a single-use vial for reconstitution with sterile, preservative-free 0.9% sodium chloride (saline).
How Jeuveau Works
Jeuveau works by temporarily blocking the release of acetylcholine at the neuromuscular junction. This inhibits the contraction of targeted facial muscles, leading to the relaxation of overactive muscle activity responsible for dynamic wrinkles. Unlike static wrinkles that are present at rest, dynamic wrinkles occur due to repeated muscle movements, such as frowning, squinting, or raising eyebrows.
By interrupting the nerve signals, Jeuveau smooths the overlying skin, reducing the appearance of facial lines and giving the face a more youthful and relaxed appearance.
Reconstitution and Dosage
Reconstitution:
To reconstitute Jeuveau, inject sterile 0.9% sodium chloride solution into the vial. Common dilution volumes range from 1 mL to 5 mL, depending on practitioner preference and desired concentration.
Example Dilution:
100 IU vial + 2.5 mL saline = 4 units per 0.1 mL
100 IU vial + 1 mL saline = 10 units per 0.1 mL
Dosage Guidelines:
Typical glabellar treatment: 20 units divided among five injection sites (4 units per site)
Other areas vary based on individual patient anatomy and desired outcome
Administration
Jeuveau should be administered intramuscularly by trained medical professionals with expertise in facial anatomy and aesthetic injection techniques. The product must be used within 24 hours after reconstitution and stored in a refrigerator at 2°C to 8°C if not used immediately.
It is crucial to ensure symmetrical placement of injections and to avoid injecting into blood vessels. Patients should be advised to remain upright and avoid massaging the treated areas for several hours following injection to reduce the risk of unwanted diffusion.
Onset and Duration
Onset of Action: Visible effects can begin within 2 to 3 days
Peak Effect: Around 7 to 14 days post-treatment
Duration: Typically lasts 3 to 5 months depending on dosage, patient metabolism, and muscle activity
Repeat treatments are recommended once the effects begin to diminish. Many patients undergo 2 to 3 sessions per year for optimal maintenance.
Safety and Side Effects
Jeuveau has been extensively studied for its safety and tolerability. In clinical trials, most adverse events were mild to moderate in severity and resolved without intervention.
Common Side Effects May Include:
Headache
Eyelid ptosis (drooping)
Localized pain at injection site
Bruising or swelling
Flu-like symptoms
Temporary muscle weakness near the injection site
Serious side effects are rare but may occur if the toxin spreads beyond the intended area. Patients should immediately seek medical attention if they experience difficulty breathing, swallowing, or speaking.
Contraindications:
Hypersensitivity to botulinum toxin ingredients
Active infection at the injection site
Neuromuscular disorders such as myasthenia gravis or ALS
Storage and Shelf Life
Before reconstitution: Store in the refrigerator at 2°C to 8°C.
After reconstitution: Use immediately or refrigerate and use within 24 hours.
Shelf life: Check expiration date on the vial label. Do not use past the expiration date.
Packaging Details
1 vial per box
Vial contains 100 Units of lyophilized PrabotulinumtoxinA-xvfs
For professional use only – not intended for home administration
Why Choose Jeuveau?
Whether you’re a cosmetic practice looking to expand your range of neuromodulators or a patient seeking high-quality wrinkle treatment, Jeuveau 100 IU offers a premium yet cost-effective solution. Its targeted design for aesthetic use, combined with advanced purification and a strong safety profile, makes it an exceptional choice in today’s competitive market.
Unlike older formulations that serve both cosmetic and medical indications, Jeuveau is focused solely on beauty—making it ideal for clinics that prioritize facial rejuvenation. The results are natural-looking, with smoother skin and a refreshed expression that still allows for subtle facial movement.
Who Can Use Jeuveau?
Jeuveau is intended for adults aged 18 to 65 who are in good general health and wish to temporarily improve the appearance of glabellar lines or other facial wrinkles. A proper medical assessment is necessary before treatment to determine suitability and ensure optimal results.
Legal Disclaimer
This product is intended for use by licensed medical professionals only. The information provided on this page is for informational purposes only and does not replace professional medical advice. All aesthetic injectable treatments carry potential risks, and individual results may vary. Always consult with a qualified healthcare provider for proper evaluation and treatment planning.
Order Jeuveau 100 IU Today
Upgrade your aesthetic practice or personal beauty regimen with Jeuveau 100 IU. With its advanced formulation, clinical efficacy, and aesthetic-only focus, Jeuveau delivers smoother, younger-looking skin with every treatment.
Order now and experience a new generation of facial rejuvenation powered by precision, purity, and performance.
