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The Master Regulator of Growth and Repair
Elevate your research with our high-pquality Fibroblast Growth Factor 2 (FGF-2), also widely known as basic FGF (bFGF) or HBGF-2. This essential, single-chain polypeptide is a cornerstone reagent in cutting-edge life science laboratories, functioning as a master regulator of cell proliferation, differentiation, and tissue repair.
As a potent member of the FGF family, our recombinant human FGF-2 is meticulously produced to ensure maximum biological activity and superior purity. It is the go-to cytokine for researchers aiming to control and optimize complex cellular environments, providing the precise signaling required to drive critical biological outcomes.
Key Applications in Advanced Research
FGF-2 is invaluable across a diverse range of demanding research applications, making it a critical component for labs focused on regenerative medicine, developmental biology, and drug discovery:
Stem Cell Culture: Essential for the long-term maintenance and propagation of undifferentiated Embryonic Stem Cells (ESCs) and Induced Pluripotent Stem Cells (iPSCs). FGF-2 helps sustain pluripotency, providing the vital cues needed for stable culture conditions without spontaneous differentiation.
Angiogenesis Studies: As a powerful angiogenic factor, FGF-2 is crucial for research into the formation of new blood vessels. It actively stimulates the proliferation and migration of endothelial cells, offering key insights into wound healing, ischemic diseases, and tumor biology.
Neural Cell Development: Supports the growth, differentiation, and survival of neural progenitor cells and neurons. Researchers utilize FGF-2 to explore neural function, repair, and the underlying mechanisms of neurodegenerative disorders.
Mesenchymal Cell Proliferation: Promotes the growth of a wide array of cells from the mesodermal lineage, including fibroblasts, smooth muscle cells, and mesenchymal stromal cells (MSCs), making it central to studies on connective tissue formation and tissue engineering.
Technical Specifications & Uncompromised Quality
Our FGF-2 is produced using rigorous quality control standards to guarantee reliable and reproducible results for your most sensitive experiments.
Source: Recombinant, expressed in E. coli for a non-glycosylated, high-purity product.
Purity: Typically 98% as determined by SDS-PAGE and validated by HPLC.
Biological Activity: Lot-specific activity is measured by its ability to stimulate the proliferation of responsive cell lines (e.g., 3T3 cells), ensuring high potency.
Formulation: Supplied as a sterile-filtered, lyophilized (freeze-dried) powder.
Synonyms: basic Fibroblast Growth Factor (bFGF), Heparin-binding Growth Factor 2 (HBGF-2).
Why choose our FGF-2? Because your time and results are too valuable to risk on low-grade reagents. Our premium FGF-2 exhibits the specific heparin-binding affinity and receptor (FGFR) activation profile critical for authentic signaling pathways, providing the consistency your high-stakes research demands.
Storage and Handling for Maximum Stability
To maintain the exceptional quality and potency of the peptide, please adhere to the following storage guidelines:
Lyophilized: Stable for up to 12 months when stored desiccated at 20C to 80C.
Reconstitution: Reconstitute with sterile, neutral buffer containing a carrier protein (e.g., 0.1% BSA).
Working Aliquots: Store reconstituted working aliquots at 20C to 80C. Avoid repeated freeze-thaw cycles to prevent degradation and loss of activity.
⚠️ For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Ready to accelerate your discoveries? Add this essential, premium-grade FGF-2 to your lab inventory today.